Unless you really want to breed your female cat, you’d be wise to have her spayed. An unspayed
female, even if kept indoors all the time, may manage to get loose and get pregnant. (Conversely, amorous tomcats can be clever and persistent in making their way to a female in heat.) In the situation where a female has mated and the owner does not want her to have kittens, the drug estradiol cypionate (ECP) can be administered within forty hours after
mating.
